Estrogen receptor beta in prostate cancer: friend or foe?
نویسندگان
چکیده
منابع مشابه
Beta-blockers: friend or foe in asthma?
BACKGROUND AND AIM Recently, β-blockers have been suggested as a potential maintenance treatment option for asthma. The aim of this review is to provide an overview of the current knowledge of the potential benefits and risks of β-blocker therapy for asthma. METHOD Systematic literature review. RESULTS No significant increase in the number of patients requiring rescue oral corticosteroid fo...
متن کاملGlucocorticoids and prostate cancer treatment: friend or foe?
Glucocorticoids have been used in the treatment of prostate cancer to slow disease progression, improve pain control and offset side effects of chemo- and hormonal therapy. However, they may also have the potential to drive prostate cancer growth via mutated androgen receptors or glucocorticoid receptors (GRs). In this review we examine historical and contemporary use of glucocorticoids in the ...
متن کاملProstate-specific antigen screening: friend or foe?
Prostate cancer is the most frequently diagnosed cancer among men in the United States. The prostate-specific antigen (PSA) blood test is the most commonly utilized test to detect early prostate malignancy. Elevated PSA levels suggest to providers the possibility that their patients are at a higher statistical risk of harboring asymptomatic, organ-confined prostate cancer. Although PSA testing ...
متن کاملAMPK in cancer: Tumor friend or foe?
AMP-activated protein kinase (AMPK) is a downstream target of the tumor suppressor and serine/threonine kinase, LKB1. LKB1 phosphorylates conserved threonine residues in the activation loops not only of AMPK but also of several AMPK-related kinases, activating all of them. AMPK (but not the AMPK-related kinases) is switched on in an LKB1-dependent manner by energy stress, and acts to conserve A...
متن کاملPGC1α: Friend or Foe in Cancer?
The PGC1 family (Peroxisome proliferator-activated receptor γ (PPARγ) coactivators) of transcriptional coactivators are considered master regulators of mitochondrial biogenesis and function. The PGC1α isoform is expressed especially in metabolically active tissues, such as the liver, kidneys and brain, and responds to energy-demanding situations. Given the altered and highly adaptable metabolis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrine-Related Cancer
سال: 2014
ISSN: 1351-0088,1479-6821
DOI: 10.1530/erc-13-0508